Genise L. Nelson was born March 5, 1955 to John and Gloria Hayes-Nelson. She was the sixth child born along with her twin. Genise accepted Christ at the age of nine years old at the Second Baptist Church under the leadership of Reverend Samuel H. James. She continued her Christian journey attending Lilly Of The Valley Missionary Baptist Church in August of 1996. Genise received her education in the San Antonio Public School System. She entered the workforce working as a Licensed Phlebotomist at Downtown Baptist Hospital for ten years.